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Large Quantitative Models — AI grounded in physics, chemistry, and biology for defense, biotech, and materials
HQ: Palo Alto, CA, United States | Founded: 2022 | Employees: ~200 (est.) | Stage: Late Stage VC ($5.75B valuation) | Website: https://www.sandboxaq.com
SandboxAQ started inside Alphabet around 2016 as 'Sandbox,' an AI-and-quantum moonshot, and spun out as an independent company in March 2022 with Eric Schmidt as chairman and Jack Hidary as CEO. Its thesis: the next wave of AI value lies not in language models trained on internet text but in Large Quantitative Models — neural systems trained on equations, simulations, and experimental data from physics, chemistry, and biology.
The product portfolio makes the thesis concrete. Synthesis generates AI-based synthetic data and manages cryptographic inventory for post-quantum migration — it is used by the U.S. Navy. AQNav pairs quantum magnetometers with AI to read Earth's magnetic crust for GPS-denied navigation, and has been trialed with the U.S. Air Force and aerospace partners including Air
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